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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345497'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345497
PNG
(Propane-1-sulfonic acid [2-(2- chloro-6-ethyl-phen...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(Cl)cccc2CC)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H25ClN4O4S/c1-5-10-32(29,30)26-19-12-18(16-11-14(3)21(28)27(4)13-16)24-22(25-19)31-20-15(6-2)8-7-9-17(20)23/h7-9,11-13H,5-6,10H2,1-4H3,(H,24,25,26)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair