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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345504'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345504
PNG
(Propane-2-sulfonic acid [6-(1- cyclopropylmethyl-5...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(CC2CC2)c1
Show InChI InChI=1S/C23H24F2N4O4S/c1-13(2)34(31,32)28-21-10-19(16-8-14(3)22(30)29(12-16)11-15-4-5-15)26-23(27-21)33-20-7-6-17(24)9-18(20)25/h6-10,12-13,15H,4-5,11H2,1-3H3,(H,26,27,28)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair