BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345515'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345515
PNG
(Propane-1-sulfonic acid [6-(2,4- dichloro-6-methyl...)
Show SMILES CCCS(=O)(=O)Nc1cc(Oc2c(C)cc(Cl)cc2Cl)nc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C21H22Cl2N4O4S/c1-5-6-32(29,30)26-17-10-18(31-19-12(2)8-15(22)9-16(19)23)25-20(24-17)14-7-13(3)21(28)27(4)11-14/h7-11H,5-6H2,1-4H3,(H,24,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair