BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345569'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345569
PNG
(Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-ox...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C22H22ClN5O4S/c1-4-5-9-33(30,31)27-19-11-18(16-10-17(23)21(29)28(3)13-16)25-22(26-19)32-20-14(2)7-6-8-15(20)12-24/h6-8,10-11,13H,4-5,9H2,1-3H3,(H,25,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair