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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345570'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345570
PNG
(3-Fluoro-propane-1-sulfonic acid [2- (2-cyano-6-me...)
Show SMILES Cc1cccc(C#N)c1Oc1nc(NS(=O)(=O)CCCF)cc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H22FN5O4S/c1-14-6-4-7-16(12-24)20(14)32-22-25-18(17-10-15(2)21(29)28(3)13-17)11-19(26-22)27-33(30,31)9-5-8-23/h4,6-7,10-11,13H,5,8-9H2,1-3H3,(H,25,26,27)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair