BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345580'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345580
PNG
(Propane-2-sulfonic acid [6-(1- methyl-6-oxo-1,6-di...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C19H24N6O4S/c1-11(2)30(27,28)23-16-9-15(14-7-8-17(26)24(5)10-14)20-19(21-16)29-18-12(3)22-25(6)13(18)4/h7-11H,1-6H3,(H,20,21,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair