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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345604'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345604
PNG
(N-(2-(2-cyano-6-methylphenoxy)-6- (1-methyl-6-oxo-...)
Show SMILES Cc1cccc(C#N)c1Oc1nc(NS(=O)(=O)CCC(F)(F)F)cc(n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H18F3N5O4S/c1-13-4-3-5-14(11-25)19(13)33-20-26-16(15-6-7-18(30)29(2)12-15)10-17(27-20)28-34(31,32)9-8-21(22,23)24/h3-7,10,12H,8-9H2,1-2H3,(H,26,27,28)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair