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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345607'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345607
PNG
(N-(6-(1,5-dimethyl-6-oxo-1,6- dihydropyridin-3-yl)...)
Show SMILES CC(C)COc1nc(NS(=O)(=O)C(C)C)cc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C18H26N4O4S/c1-11(2)10-26-18-19-15(14-7-13(5)17(23)22(6)9-14)8-16(20-18)21-27(24,25)12(3)4/h7-9,11-12H,10H2,1-6H3,(H,19,20,21)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair