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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345757'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345757
PNG
(5-{2-(2-Fluoro-6-methyl-phenoxy)- 6-[(pyridin-2-yl...)
Show SMILES Cc1cccc(F)c1Oc1nc(NCc2ccccn2)cc(n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C23H20FN5O2/c1-15-6-5-8-18(24)22(15)31-23-27-19(16-9-10-21(30)29(2)14-16)12-20(28-23)26-13-17-7-3-4-11-25-17/h3-12,14H,13H2,1-2H3,(H,26,27,28)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair