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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345799'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345799
PNG
(N-(2-(2,4-difluoro-6- methylphenoxy)-6-(1-methyl-6...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cc(F)cc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H20F2N4O4S/c1-4-7-31(28,29)25-17-10-16(13-5-6-18(27)26(3)11-13)23-20(24-17)30-19-12(2)8-14(21)9-15(19)22/h5-6,8-11H,4,7H2,1-3H3,(H,23,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair