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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345810'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345810
PNG
(N-(2-isopropoxy-6-(1-methyl-6-oxo- 1,6-dihydropyri...)
Show SMILES CC(C)Oc1nc(NS(=O)(=O)c2ccccc2)cc(n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C19H20N4O4S/c1-13(2)27-19-20-16(14-9-10-18(24)23(3)12-14)11-17(21-19)22-28(25,26)15-7-5-4-6-8-15/h4-13H,1-3H3,(H,20,21,22)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair