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Found 4 Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM50200445'
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataIC50:  20nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged CBP measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataIC50:  22nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataIC50:  410nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated human CBP expressed in HEK293 cells after overnight incubation by BRE...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataEC50:  910nMAssay Description:Inhibition of CBP in human MV-4-11 cells assessed as decrease in MYC expression incubated for 4 hrs measured by luminescence methodMore data for this Ligand-Target Pair