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Found 3 Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292572'
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292572((S)-N-(2-(diethylamino)propyl)-2-(methylamino)-6-(...)
Affinity DataIC50:  0.0500nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292572((S)-N-(2-(diethylamino)propyl)-2-(methylamino)-6-(...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of recombinant human full length His-tagged CaMK2delta expressed in baculovirus using Biotin labelled STK1 as substrate after 1 hr in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292572((S)-N-(2-(diethylamino)propyl)-2-(methylamino)-6-(...)
Affinity DataEC50:  21.1nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent