BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calmodulin-domain protein kinase 1 (CDPK1)' and Ligand = 'BDBM286282'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calmodulin-domain protein kinase 1 (CDPK1)


(Toxoplasma gondii)
BDBM286282
PNG
(US9518026, Example 75)
Show SMILES NC(=O)c1c(N)n(nc1-c1ccc2nc(OC3CCC3)ccc2c1)C1CCC1
Show InChI InChI=1S/C21H23N5O2/c22-20-18(21(23)27)19(25-26(20)14-3-1-4-14)13-7-9-16-12(11-13)8-10-17(24-16)28-15-5-2-6-15/h7-11,14-15H,1-6,22H2,(H2,23,27)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



University of Washington Through its Center For Commercialization

US Patent


Assay Description
Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...


US Patent US9518026 (2016)

More data for this
Ligand-Target Pair