BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM321054'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM321054
PNG
(US10174040, Example 138 | [(1R,2S,4R)-4-[4-Amino-5...)
Show SMILES Cc1ccc(Cn2cc(cn2)-c2cn([C@H]3C[C@H](O)[C@@H](COS(N)(=O)=O)C3)c3ncnc(N)c23)cc1C
Show InChI InChI=1S/C24H29N7O4S/c1-14-3-4-16(5-15(14)2)9-30-10-18(8-29-30)20-11-31(24-22(20)23(25)27-13-28-24)19-6-17(21(32)7-19)12-35-36(26,33)34/h3-5,8,10-11,13,17,19,21,32H,6-7,9,12H2,1-2H3,(H2,25,27,28)(H2,26,33,34)/t17-,19-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...


US Patent US10174040 (2019)

More data for this
Ligand-Target Pair