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Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50428400'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataKi:  395nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataKi:  395nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataKi:  1.43E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataIC50:  1.43E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CA-2 (unknown origin) after 15 mins by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed