BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform alpha' and Ligand = 'BDBM50390497'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I isoform alpha


(Homo sapiens (Human))
BDBM50390497
PNG
(CHEMBL2071611)
Show SMILES Cn1cc(cn1)-c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1
Show InChI InChI=1S/C18H14N6/c1-24-11-14(10-20-24)13-3-5-15(6-4-13)21-18-22-16-7-2-12(9-19)8-17(16)23-18/h2-8,10-11H,1H3,(H2,21,22,23)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.54E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha by Lance assay


Bioorg Med Chem Lett 22: 5392-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.046
BindingDB Entry DOI: 10.7270/Q2CF9R6Q
More data for this
Ligand-Target Pair