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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-8' and Ligand = 'BDBM10548'
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Canada

LigandPNGBDBM10548((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[1-(2,5-dimethox...)
Affinity DataIC50:  6.60E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Canada

LigandPNGBDBM10548((3S)-5-(benzylsulfanyl)-3-[(2S)-2-[1-(2,5-dimethox...)
Affinity DataIC50:  7.91E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed