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Found
1
Enz. Inhib. hit(s) with Target = 'Cathepsin D' and Ligand = 'BDBM335431'
Target
Cathepsin D
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM335431
(8-((4-((3R,6S)-5-amino-6- cyclopropyl-3,6-dimethyl...)
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Affinity Data
Ki: 6.65E+3nM
Assay Description:
The following reagents were used in this assay: Na+-Acetate pH 5.0; 1% Brij-35; Dimethyl Sulfoxide (DMSO); Purified human Cathepsin-D (>95% pure); As...
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Target Info
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NCI pathway
Reactome pathway
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Ligand Info
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Details
US Patent
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