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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin S' and Ligand = 'BDBM50401768'
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50401768(CHEMBL2207560)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of cathepsin S using FR-aminoluciferin as substrate preincubated for 15 mins before substrate addition measured after 1 hr by luminescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50401768(CHEMBL2207560)
Affinity DataIC50:  10nMAssay Description:Inhibition of cathepsin S-mediated antigen presentation in B/T hybridoma cells assessed as IL-2 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed