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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM12553'
TargetCoagulation factor X(Homo sapiens (Human))
Gsk

LigandPNGBDBM12553(6-chloro-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxop...)
Affinity DataKi:  285nM ΔG°:  -37.0kJ/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Gsk

LigandPNGBDBM12553(6-chloro-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxop...)
Affinity DataKi:  285nM ΔG°:  -37.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed