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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50144106'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50144106
PNG
(CHEMBL65146 | {4-(5-Chloro-1H-indole-2-sulfonyl)-1...)
Show SMILES COC(=O)CC1CN(CCN1C(=O)c1ccc(cc1)C1=NCCN1C)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1/C26H28ClN5O5S/c1-30-10-9-28-25(30)17-3-5-18(6-4-17)26(34)32-12-11-31(16-21(32)15-24(33)37-2)38(35,36)23-14-19-13-20(27)7-8-22(19)29-23/h3-8,13-14,21,29H,9-12,15-16H2,1-2H3
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Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Coagulation factor X was determined


Bioorg Med Chem Lett 14: 2073-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.049
BindingDB Entry DOI: 10.7270/Q2P84B98
More data for this
Ligand-Target Pair