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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM285860'
Target
Coagulation factor XI
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM285860
(US10081617, Example 9)
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Affinity Data
IC50: 0.320nM
pH: 7.4
Assay Description:
Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...
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Target Info
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Ligand Info
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US Patent
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