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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM285925'
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM285925(7-(5-(6-amino-2-chloropyridin-3-yl)-1H-imidazol-2-...)
Affinity DataIC50:  41.9nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent