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Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM298340'
Target
Coagulation factor XI
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM298340
(US10123995, Example 18)
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Affinity Data
IC50: 9.45E+3nM
Assay Description:
The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...
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