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Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM335418'
TargetCoagulation factor XI(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM335418(4-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...)
Affinity DataIC50:  1.60nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM335418(4-(2-{(3S)-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]...)
Affinity DataIC50:  1.60nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent