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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM394135'
Target
Coagulation factor XI
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM394135
(US9975874, Example 8)
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Affinity Data
IC50: 41nM
Assay Description:
Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...
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Ligand Info
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US Patent
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