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Found 4 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM439326'
TargetCoagulation factor XI(Homo sapiens (Human))
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439326((R)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  1.82E+3nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439326((R)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  1.82E+3nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439326((R)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  4.83E+3nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jinagsu Hengrui Medicine

US Patent
LigandPNGBDBM439326((R)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50:  4.83E+3nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent