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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM159294'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159294
PNG
(US10093663, Example 8 | US9682968, Example-8)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C23H27N3O/c1-15-13-16(2)22-19(10-11-25-22)20(15)14-26-12-4-3-5-21(26)17-6-8-18(9-7-17)23(24)27/h6-11,13,21,25H,3-5,12,14H2,1-2H3,(H2,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.710n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159294
PNG
(US10093663, Example 8 | US9682968, Example-8)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C23H27N3O/c1-15-13-16(2)22-19(10-11-25-22)20(15)14-26-12-4-3-5-21(26)17-6-8-18(9-7-17)23(24)27/h6-11,13,21,25H,3-5,12,14H2,1-2H3,(H2,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 710n/an/an/an/a7.425



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US10093663 (2018)

More data for this
Ligand-Target Pair