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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM160501'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM160501
PNG
(US10093663, Example 38 | US9682968, Example-38)
Show SMILES CNC(=O)c1ccc(cc1)[C@@H]1C[C@H](CCN1Cc1c(OC)cc(C)c2[nH]ccc12)OC
Show InChI InChI=1S/C25H31N3O3/c1-16-13-23(31-4)21(20-9-11-27-24(16)20)15-28-12-10-19(30-3)14-22(28)17-5-7-18(8-6-17)25(29)26-2/h5-9,11,13,19,22,27H,10,12,14-15H2,1-4H3,(H,26,29)/t19-,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160501
PNG
(US10093663, Example 38 | US9682968, Example-38)
Show SMILES CNC(=O)c1ccc(cc1)[C@@H]1C[C@H](CCN1Cc1c(OC)cc(C)c2[nH]ccc12)OC
Show InChI InChI=1S/C25H31N3O3/c1-16-13-23(31-4)21(20-9-11-27-24(16)20)15-28-12-10-19(30-3)14-22(28)17-5-7-18(8-6-17)25(29)26-2/h5-9,11,13,19,22,27H,10,12,14-15H2,1-4H3,(H,26,29)/t19-,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 130n/an/an/an/a7.425



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US10093663 (2018)

More data for this
Ligand-Target Pair