BindingDB PrimarySearch

Found 12 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1' and Ligand = 'BDBM5655'

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

Ki: 40nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

Ki: 70nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 10nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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Details PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of cdk1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Cyclin-dependent kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)

IC50: 330nMAssay Description:Inhibition of Cdk1/cyclin BMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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Details Article PubMed DrugBank

Filter my 12 hits

Targets 1▿
- Cyclin-dependent kinase 1 12
Publications 12▿
- J Med Chem 63: 13228-13257 (2020) 1
- J Nat Prod 79: 616-28 (2016) 1
- Bioorg Med Chem 27: 677-685 (2019) 1
- Bioorg Med Chem 16: 7128-33 (2008) 1
- J Med Chem 65: 893-921 (2022) 1
- AAPS J 8: 204-21 (2006) 1
- J Med Chem 56: 660-70 (2013) 1
- J Med Chem 65: 935-954 (2022) 1
- Eur J Med Chem 183: (2019) 1
- Eur J Med Chem 172: 143-153 (2019) 1
- Nat Chem Biol 4: 357-65 (2008) 1
- Eur J Med Chem 142: 424-458 (2017) 1
Institutions 11▿
- China Pharmaceutical University 2
- Centro De Investigaciones Biol�Gicas Margarita Salas (Csic) 1
- Csir-Indian Institute Of Integrative Medicine 1
- Dalian University Of Technology 1
- Tianjin University Of Science And Technology 1
- Monash University (Parkville Campus) 1
- University Of Oxford 1
- Georgetown University 1
- University Of Padova 1
- Nerviano Medical Sciences Oncology 1
- Central University Of Punjab 1
Affinity: 10 to 3.3E+2 nM▿
- Ki 2
- IC50 10
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1