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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM112466'
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM112466
(US8623885, 7)
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Affinity Data
IC50: 52.4nM
pH: 7.4
Assay Description:
The CDK4 and CDK1 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a filtration kinase assay. The compounds, kinase and substrat...
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Ligand Info
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