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Found 1 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM112496'
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM112496(US8623885, 37)
Affinity DataIC50:  3nMpH: 7.4Assay Description:The CDK4 and CDK1 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a filtration kinase assay. The compounds, kinase and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent