Affinity DataIC50: 520nMAssay Description:Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK7 in human HT29 cells assessed as reduction in RNA polymerase 2 expressionMore data for this Ligand-Target Pair