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Found 1 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50361158'
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50361158(CHEMBL4162429)
Affinity DataIC50:  17nMAssay Description:Inhibition of CDK8 in human HepG2 cells assessed as reduction in IFNgamma-induced STAT1 phosphorylation at S727 measured after 18 hrs by Western blot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed