BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclophilin D (CypD)' and Ligand = 'BDBM140006'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclophilin D (CypD)


(Homo sapiens (Human))
BDBM140006
PNG
(US8901295, F712)
Show SMILES CSc1ccccc1C1CCCN1C(=O)C(CC(C)C)NC(=O)NCc1ccc(N)cc1
Show InChI InChI=1S/C25H34N4O2S/c1-17(2)15-21(28-25(31)27-16-18-10-12-19(26)13-11-18)24(30)29-14-6-8-22(29)20-7-4-5-9-23(20)32-3/h4-5,7,9-13,17,21-22H,6,8,14-16,26H2,1-3H3,(H2,27,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.00E+3n/an/an/an/a7.820



Institut National de la Sante et de la Recherche Medicale (INSERM); Universite Montpellier 1; Universite Paris-EST Creteil val de Marne; Assistance Publique-Hopitaux de Paris; Centre National de la Recherche Scientifique

US Patent


Assay Description
Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...


US Patent US8901295 (2014)


BindingDB Entry DOI: 10.7270/Q2R49PGS
More data for this
Ligand-Target Pair