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Found 2 Enz. Inhib. hit(s) with Target = 'Cystine/glutamate transporter' and Ligand = 'BDBM50355006'
TargetCystine/glutamate transporter(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50355006(CHEMBL1834958)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystine/glutamate transporter(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50355006(CHEMBL1834958)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed