Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM287634'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Viamet Pharmaceuticals (Bermuda)
US Patent
Affinity DataIC50: 750nMAssay Description:V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Viamet Pharmaceuticals (Bermuda)
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair