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Found
1
Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2C8' and Ligand = 'BDBM298452'
Target
Cytochrome P450 2C8
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM298452
((1S,2S)-2-(5-{(R)-7-Fluoro-4-[4-(3-hydroxy-3-methy...)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...
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Target Info
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Reactome pathway
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Ligand Info
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Details
US Patent
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