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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2C8' and Ligand = 'BDBM320017'
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM320017(Trans Isomer 1; 3- (5-chloro-1,3- thiazol-2-yl)-5-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Human liver microsomes (pooled, >30 male and female donors) were incubated with individual CYP isoform-selective standard probes (phenacetin for CYP1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM320017(Trans Isomer 1; 3- (5-chloro-1,3- thiazol-2-yl)-5-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Use of in vitro assays to evaluate the inhibition potential of new drug candidates towards CYP-mediated metabolism has been shown to be effective as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent