Found 3 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM235777' TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 23.6nM ΔG°: -44.3kJ/mole IC50: 47.9nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 23.6nM ΔG°: -44.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 248nM ΔG°: -38.3kJ/mole IC50: 484nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
