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Found 8 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50061642'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  0.350nMAssay Description:Agonistic activity towards dopamine D2 receptor using radioligand [3H]-quinpirole in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  0.400nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  0.400nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  4.80nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  5.70nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  5.70nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity at human Dopamine receptor D2 (hD2) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061642((S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]d...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed