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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase beta' and Ligand = 'BDBM50027115'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase beta


(Mus musculus)
BDBM50027115
PNG
(2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18...)
Show SMILES CCCN(CCC)\N=C\c1cc2c3C(=O)C4(C)Oc3c(C)c(O)c2c(O)c1NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C(C)C(OC)\C=C\O4
Show InChI InChI=1S/C44H61N3O11/c1-12-18-47(19-13-2)45-22-30-21-31-33-38(51)28(8)41-34(31)42(53)44(10,58-41)56-20-17-32(55-11)25(5)40(57-29(9)48)27(7)37(50)26(6)36(49)23(3)15-14-16-24(4)43(54)46-35(30)39(33)52/h14-17,20-23,25-27,32,36-37,40,49-52H,12-13,18-19H2,1-11H3,(H,46,54)/b15-14+,20-17+,24-16-,45-22+
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MMDB

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Similars

Article
PubMed
n/an/a 0.0000450n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit mouse beta DNA polymerase


J Med Chem 23: 256-61 (1980)


Article DOI: 10.1021/jm00177a009
BindingDB Entry DOI: 10.7270/Q2XD10PG
More data for this
Ligand-Target Pair