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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase beta' and Ligand = 'BDBM50027118'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase beta


(Mus musculus)
BDBM50027118
PNG
(26-diethylaminomethyl-2,15,17,29-tetrahydroxy-11-m...)
Show SMILES CCN(CC)Cc1cc2c3C(=O)C4(C)Oc3c(C)c(O)c2c(O)c1NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C(C)C(OC)\C=C\O4
Show InChI InChI=1S/C42H58N2O11/c1-12-44(13-2)20-28-19-29-31-36(48)26(8)39-32(29)40(50)42(10,55-39)53-18-17-30(52-11)23(5)38(54-27(9)45)25(7)35(47)24(6)34(46)21(3)15-14-16-22(4)41(51)43-33(28)37(31)49/h14-19,21,23-25,30,34-35,38,46-49H,12-13,20H2,1-11H3,(H,43,51)/b15-14+,18-17+,22-16-
PDB
MMDB

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Similars

Article
PubMed
n/an/a 0.00110n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit mouse beta DNA polymerase


J Med Chem 23: 256-61 (1980)


Article DOI: 10.1021/jm00177a009
BindingDB Entry DOI: 10.7270/Q2XD10PG
More data for this
Ligand-Target Pair