Found 2 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50259215' TargetDNA topoisomerase 1(Escherichia coli (strain K12))
The Florida International University Board Of Trustees
US Patent
The Florida International University Board Of Trustees
US Patent
Affinity DataIC50: 240nMAssay Description:The relaxation activity of E. coli topoisomerase I was assayed in a buffer containing 10 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mg/mL gelatin, and 0.5 ...More data for this Ligand-Target Pair
TargetDNA topoisomerase 1(Homo sapiens (Human))
The Florida International University Board Of Trustees
US Patent
The Florida International University Board Of Trustees
US Patent
Affinity DataIC50: 7.80E+3nMAssay Description:Human topoisomerase I relaxation assays were carried out with 0.5 U of enzyme in reaction buffer supplied by the manufacturer. The enzyme was mixed w...More data for this Ligand-Target Pair
