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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50078465'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078465(6-[(4-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50:  55.6nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078465(6-[(4-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50:  55.6nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078465(6-[(4-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50:  95.4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078465(6-[(4-Methoxy-phenylamino)-methyl]-5-methyl-pyrido...)
Affinity DataIC50:  95.4nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed