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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50310338'
TargetDihydrofolate reductase(Mycobacterium avium)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50310338(CHEMBL596672 | N-[4-[(2,4-Diamino-5-methyl-furo[2,...)
Affinity DataIC50:  9.73nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50310338(CHEMBL596672 | N-[4-[(2,4-Diamino-5-methyl-furo[2,...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50310338(CHEMBL596672 | N-[4-[(2,4-Diamino-5-methyl-furo[2,...)
Affinity DataIC50:  4.00E+3nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50310338(CHEMBL596672 | N-[4-[(2,4-Diamino-5-methyl-furo[2,...)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed