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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50351195'
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics, San Diego, Ca 92121, United States.

Curated by ChEMBL
LigandPNGBDBM50351195(CHEMBL1818123)
Affinity DataKi:  0.850nMAssay Description:Inhibition of Staphylococcus aureus DHFR assessed as oxidation of NADPH using dihydrofolate as substrate pre-incubated for 10 mins before substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics, San Diego, Ca 92121, United States.

Curated by ChEMBL
LigandPNGBDBM50351195(CHEMBL1818123)
Affinity DataKi:  22.2nMAssay Description:Inhibition of human DHFR assessed as oxidation of NADPH using dihydrofolate as substrate pre-incubated for 10 mins before substrate addition by spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed