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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase' and Ligand = 'BDBM50201905'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotate dehydrogenase


(Homo sapiens (Human))
BDBM50201905
PNG
(3-hydroxy-2-(4-phenoxyphenyl)quinoline-4-carboxyli...)
Show SMILES OC(=O)c1c(O)c(nc2ccccc12)-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C22H15NO4/c24-21-19(22(25)26)17-8-4-5-9-18(17)23-20(21)14-10-12-16(13-11-14)27-15-6-2-1-3-7-15/h1-13,24H,(H,25,26)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DHOD expressed in Escherichia coli


J Med Chem 50: 21-39 (2007)


Article DOI: 10.1021/jm0602256
BindingDB Entry DOI: 10.7270/Q2Z60PVV
More data for this
Ligand-Target Pair