BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337364'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337364
PNG
(4-[4-(4,6-Dimethylpyrimidin-5-yl)-3-methylphenoxy]...)
Show SMILES CC1=C(C(C)=[N](C)C=N1)c1ccc(Oc2nccc3N(CCc23)C2CCCCO2)cc1C
Show InChI InChI=1S/C26H31N4O2/c1-17-15-20(8-9-21(17)25-18(2)28-16-29(4)19(25)3)32-26-22-11-13-30(23(22)10-12-27-26)24-7-5-6-14-31-24/h8-10,12,15-16,24H,5-7,11,13-14H2,1-4H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
78.1n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)

More data for this
Ligand-Target Pair